What are T-Cell Modulators?

T-Cell Modulator is a molecule that reinforces and balances the immune system through regulation of it’s signaling properties, based on the specific needs of the body. It stimulates the immune system’s ability to recognize foreign substances past and present, allowing for a quicker and more efficient response to similar threats to the overall state of health. T-Cell Modulator also “educates” or “activates” immature immune cells in a specific way. This helps reduce potential risk, while providing the immune system with a plan of action, all the while accelerating foreign body recognition. T Cell Modulator (T-Cell Modulator®) is a leukocyte extract manufactured through proprietary methodology, described in part as a small polypeptide-chain, small enough not to be perceived as a threat by the immune system, but with specific properties that help it bind to TLR2 and TLR4 receptors found in immune cells.

Diabetes is actually a group of diseases characterized by abnormally high levels of the sugar glucose in the bloodstream. This excess glucose is responsible for most of the complications of diabetes, which include blindness, kidney failure, heart disease, stroke, neuropathy, and amputations.

Type 1 diabetes, also known as juvenile-onset diabetes, typically affects children and young adults. Diabetes develops when the body's immune system sees its own cells as foreign and attacks and destroys them. As a result, the islet cells of the pancreas, which normally produce insulin, are destroyed. In the absence of insulin, glucose cannot enter the cell and glucose accumulates in the blood.

Type 2 diabetes, also called adult-onset diabetes, tends to affect older, sedentary, and overweight individuals with a family history of diabetes. Type 2 diabetes occurs when the body cannot use insulin effectively. This is called insulin resistance and the result is the same as with type 1 diabetes—a build up of glucose in the blood.

How does T-Cell Modulator work for Type 1 Diabetes patients ?

T-Cell Modulator in binding to TLR receptors, have the ability to modulate (up or down regulate) specific immune system activities, which can be attributed to the immune system overreacting in an attempt to re-establish balance, as is the case in type 1 diabetes.

How does T-Cell Modulator work for Type 2 Diabetes patients ?

T-Cell Modulator also offers important support for Type diabetes 2, specifically in combating inflammation. Studies have shown that there are two specific ways in which inflammation affects insulin resistance. Chronic inflammation directly affects insulin resistance (increasing it) by de-regulating and altering the activities of TLR4 receptors, which stops glucose from entering the cell. As a consequence, there is intracellular inflammatory activity, a cascade of specific signals in reaction to the chronic inflammation which make the cell even less capable of absorbing and responding to insulin, thereby not only increasing blood insulin levels, but also de-regulating glucose uptake and forcing the body to overcompensate for both.

More about TLR2 and TLR4 receptors

In regulating immune activity by directly influencing cell activity, as well as binding to TLR2 and TLR4 receptors, T-Cell Modulator directs the body’s immune activity away from the over-compensatory effect found in auto-immune modulated diabetes cases, as well as resolving the inflammatory issue that plagues both type 1 and type 2 diabetics

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